- Ribosome occupancy profiles are conserved between structurally and evolutionarily related yeast domains
- Mouse Quantitative Proteomics Knowledgebase: reference protein concentration ranges in 20 mouse tissues using 5000 quantitative proteomics assays
- A rarefaction-based extension of the LDM for testing presence-absence associations in the microbiome
- Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs
- Minimal genome-wide human CRISPR-Cas9 library
- Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
- Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs
- Minimal genome-wide human CRISPR-Cas9 library
- Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
- MBG: Minimizer-based Sparse de Bruijn Graph Construction
- VPF-Class: Taxonomic assignment and host prediction of uncultivated viruses based on viral protein families
- Genome-scale de novo assembly using ALGA
- bbeaR: an R package and framework for epitope-specific antibody profiling
- lgpr: An interpretable nonparametric method for inferring covariate effects from longitudinal Data
- SWOTein: a structure-based approach to predict stability Strengths and Weaknesses of prOTEINs
- TIPP2: metagenomic taxonomic profiling using phylogenetic markers
- IsoMiRmap—fast, deterministic, and exhaustive mining of isomiRs from short RNA-seq datasets
- PrInCE: an R/bioconductor package for protein-protein interaction network inference from co-fractionation mass spectrometry data
- DeepSurf: A surface-based deep learning approach for the prediction of ligand binding sites on proteins
- Compression of quantification uncertainty for scRNA-seq counts
Whats new in Bioinformatics
Genome Biology
- Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs
- Minimal genome-wide human CRISPR-Cas9 library
- Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
- Pair consensus decoding improves accuracy of neural network basecallers for nanopore sequencing
- MethylationToActivity: a deep-learning framework that reveals promoter activity landscapes from DNA methylomes in individual tumors
- SPIN reveals genome-wide landscape of nuclear compartmentalization
- Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals
- High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts
- A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity
- The variant call format provides efficient and robust storage of GWAS summary statistics