- Using tree-based methods for detection of gene-gene interactions in the presence of a polygenic signal: simulation study with application to educational attainment in the Generation Scotland Cohort Study
- 3DPatch: fast 3D structure visualization with residue conservation
- Predicting clone genotypes from tumor bulk sequencing of multiple samples
- 13Check_RNA: A tool to evaluate 13C chemical shifts assignments of RNA
- Estimating pseudocounts and fold changes for digital expression measurements
- GWASinlps: Nonlocal prior based iterative SNP selection tool for genome-wide association studies
- Modelling Signalling Networks from Perturbation Data
- HUME: Large-scale Detection of Causal Genetic Factors of Adverse Drug Reactions
- Prediction of kinetics of protein folding with non-redundant contact information
- Accurate Prediction of Protein Contact Maps by Coupling Residual Two-Dimensional Bidirectional Long Short-Term Memory with Convolutional Neural Networks
- panISa: Ab initio detection of insertion sequences in bacterial genomes from short read sequence data
- SONiCS: PCR stutter noise correction in genome-scale microsatellites
- mol2sphere: Spherical Decomposition of Multi-Domain Molecules for Visualization and Coarse Grained Spatial Modeling
- Grimon: Graphical interface to visualize multi-omics networks
- MolArt: A molecular structure annotation and visualization tool
- htsget: a protocol for securely streaming genomic data
- ICBdocker: a Docker image for proteome annotation and visualization
- Deep convolutional networks for quality assessment of protein folds
- PASTA for Proteins
- Operon-mapper: A Web Server for Precise Operon Identification in Bacterial and Archaeal Genomes
Whats new in Bioinformatics
Genome Biology
- dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
- Diversification and independent domestication of Asian and European pears
- Tensorial blind source separation for improved analysis of multi-omic data
- Hundreds of novel composite genes and chimeric genes with bacterial origins contributed to haloarchaeal evolution
- Dissecting an adiposity locus with an arsenal of genomics
- SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology
- MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis
- A major locus controls local adaptation and adaptive life history variation in a perennial plant
- Vex-seq: high-throughput identification of the impact of genetic variation on pre-mRNA splicing efficiency
- RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum