Bioinformatics, PU

Database tools

Databases and software tools developed in house under the guidance of faculty members are being validated by the corresponding faculty and are published in reputed Journal. The same databases and software tools are hosted in our servers under the domain name bicpu.edu.in. There are 15 research databases and software tools are hosted and being maintained by the Technical Support Team of the Bioinformatics Centre.

Muthukumaran J, Jayakanthan M, Chandrasekar S and Mathur PP

Bind-Predict is resource of database and software tools for identifying zinc finger protein binding motifs in mammalian genomes. The bind-predict has a user friendly interface tool named as Bind-predictdB and a database named as Bind-predictdB that are used to predict zinc finger binding sites in the user given input DNA sequence. Citation: Muthukumaran J, Jayakanthan M, Chandrasekar S, Mathur P.P. Bind-Predict: An algorithm for identifying zinc finger binding motifs in DNA sequences. J.Comp. Biol. Bioinfo. Res. 2011, 3(7): 91-102. [Journal][PDF]

Om Prakash Sharma, Arindam Atanu Das, R.Krishna, M.Suresh Kumar, and Premendu P. Mathur

SEDB provides structural and Ag-Ab interaction information, through user friendly interference. Currently, database comprises 619 entries. An Epitope structure, which has been experimentally proved and available in PDB, has been added in our database. [Journal], [PDF]

Om Prakash Sharma, Ankush Jadhav, Afzal Hussain and M. Suresh Kumar

Viral Protein Database is an interactive database for three dimensional viral proteins. Our aim is to provide a comprehensive resource to the community of structural virology, with an emphasis on the description of derived data from structural biology. Currently, VPDB includes ~1,670 viral protein structures from 277 viruses with more than 465 virus strains. [Journal], [PDF]

Om Prakash Sharma, Hoti SL and Mathur PP

FILOBASE is a comprehensive resource of filariasis tools and database that provides a catalog of experimentally proven drug, drug target and EST sequences derived from various literatures and other publicly available protein sequence databases.

Om Prakash Sharma, Suresh Kumar M and Mathur PP

Immune epitope database (IEP) is an online repository that provides a catalog of experimentally proven linear T and B cell epitopes derived from various literatures listed in PubMed database and other publicly available protein sequence databases. Databases entries are collected and manually curated based on viral diseases. This computational resource can be used to identify the potential viral epitopes and its location from the protein sequence.

Arindam Atanu Das, Om Prakash Sharma, Suresh Kumar M, Krishna R and Mathur PP

Peptide Binding Protein Database (PepBind) is a derived database of available protein structures from Protein Data Bank (PDB) which bind to peptides. These proteins are further classified as per the length of the peptide, such as dipeptide binding proteins, tripeptide binding proteins, etc.

Jagajjit Sahu, Arindam Atanu Das, Krishna R and Mathur PP

MemProt is a database of comprehensive collection of membrane proteins and prediction tool for physiochemical properties. This database would be used as a primary source to the researchers working in structural and functional biology for membrane proteins. It provides sequence and structural information of membrane proteins.

Kumara Swamy Naidu C and Mathur PP

This E-Learning module of Bioinformatics/Molecular Biology contains interactive animations, structural tutorials, and critical thinking exercises. These modules can be learnt through online and also in offline, unlike the traditional teacher-centric learning method.

Jyothii V and Shanthi N

Antony TR and Nagarajan S

DrugMetZ DB, a database for CYP metabolizing drugs. The DB is implemented in MySQL, PHP and HTML. This database provides essential information about different categories of drugs and corresponding metabolizing Cytochromal isozymes present in human body. It is a user friendly database, allows user to search for various drugs and enzymes. Citation: Antony TR, Nagarajan S. DrugMetZ DB: an anthology of human drug metabolizing Chytochrome P450 enzymes. Bioinformation 2006, (7): 248-50. [PubMed], [PDF]

Ankur Chaurasia, Jyotilipsa Mohanty, Lukkani Laxman Kumar and Ayaluru Murali

CoSec (Compare Secondary structures) is a hub of online tools consisting of Predicted Secondary Structure Matching (PreSSM) and Compare Assigned Secondary Structure (CompASS). The PreSSM tool compares the secondary structure elements of a modelled protein from a PDB to the predicted secondary structure , while the tool CompASS compares the secondary structures between two PDBs of the same protein (typically the models before and after simulation/docking with a ligand/mutation).[PDF]